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impetigo

Dermatology/Infectious DiseaseIntegumentaryImmune

Summary

Impetigo is a superficial bacterial skin infection caused primarily by Staphylococcus aureus and Streptococcus pyogenes. It presents as honey-crusted lesions (non-bullous) or fluid-filled blisters (bullous) and is highly contagious, especially in children.

Detail

Impetigo is the most common bacterial skin infection in children, with two main forms: non-bullous (70% of cases) and bullous impetigo. Non-bullous impetigo typically begins as small vesicles that rupture and form characteristic honey-colored crusts, commonly affecting the face and extremities. It's usually caused by S. pyogenes or S. aureus. Bullous impetigo is caused exclusively by S. aureus strains producing exfoliative toxins A and B, presenting as larger, flaccid bullae that rupture leaving a thin rim of scale. The infection is limited to the epidermis and spreads through direct contact or fomites. Risk factors include minor trauma, poor hygiene, crowded conditions, and warm, humid climates. Complications are rare but may include cellulitis, lymphangitis, and post-streptococcal glomerulonephritis (with S. pyogenes). Treatment involves topical antibiotics (mupirocin) for localized disease or oral antibiotics (cephalexin, clindamycin) for extensive infection.

Sources

  • Fitzpatrick's Dermatology in General Medicine
  • Mandell, Douglas, and Bennett's Principles of Infectious Diseases
  • First Aid for USMLE Step 1
  • Harrison's Principles of Internal Medicine

Reviewed by AnkiBoss editorial — medical student review. Information here is for study reference only and is not medical advice. Spotted an error? Let us know.

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