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Bornholm disease

MicrobiologyMusculoskeletalRespiratoryInfectious Disease

Summary

Bornholm disease, or epidemic pleurodynia, is an acute illness caused by coxsackie B virus producing sudden severe paroxysmal chest or upper abdominal pain from inflammation of intercostal and abdominal muscles. It is also called devil's grip.

Detail

Named after the Danish island where an outbreak was described, it presents abruptly with fever and knife-like, spasmodic pain over the lower chest or upper abdomen, worsened by breathing, coughing, and movement, and coming in waves lasting minutes with pain-free intervals. A pleural friction rub may be heard, and the pain often prompts investigation for pulmonary embolism, myocardial infarction, or an acute abdomen. Symptoms usually settle within a week, though relapse after a few days is common. Because coxsackie B also causes myocarditis and pericarditis, patients should be assessed for those, and concurrent orchitis or aseptic meningitis may occur. Transmission is faecal-oral, with summer and early autumn outbreaks in families and communities. Diagnosis is clinical, supported by throat or stool PCR; chest imaging is normal, which helps exclude alternatives. Treatment is symptomatic with analgesia and NSAIDs, with caution if myocarditis is suspected. Recovery is complete.

Sources

  • Levinson Medical Microbiology and Immunology
  • Harrison's Principles of Internal Medicine

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